miércoles, 24 de noviembre de 2010

The use of opioids at the end of life: the knowledge level of Dutch physicians as a potential barrier to effective pain management

Mette L Rurup email, Christiaan A Rhodius email, Sander D Borgsteede email, Manon SA Boddaert email, Astrid GM Keijser email, H Roeline W Pasman email and Bregje D Onwuteaka-Philipsen email

BMC Palliative Care 2010


Pain is still one of the most frequently occurring symptoms at the end of life, although it can be treated satisfactorily in most cases if the physician has adequate knowledge. In the Netherlands, almost 60% of the patients with non-acute illnesses die at home where end of life care is coordinated by the general practitioner (GP); about 30% die in hospitals (cared for by clinical specialists), and about 10% in nursing homes (cared for by elderly care physicians). The research question of this study is: what is the level of knowledge of Dutch physicians concerning pain management and the use of opioids at the end of life?


A written questionnaire was sent to a random sample of physicians of specialties most often involved in end of life care in the Netherlands. The questionnaire was completed by 406 physicians, response rate 41%.


Almost all physicians were aware of the most basal knowledge about opioids, e.g. that it is important for treatment purposes to distinguish nociceptive from neuropathic pain (97%). Approximately half of the physicians (46%) did not know that decreased renal function raises plasma concentration of morphine(-metabolites) and 34% of the clinical specialists erroneously thought opioids are the favoured drug for palliative sedation. Although 91% knew that opioids titrated against pain do not shorten life, 10% sometimes or often gave higher dosages than needed with the explicit aim to hasten death. About half felt sometimes or often pressured by relatives to hasten death by increasing opioiddosage. The large majority (83%) of physicians was interested in additional education about subjects related to the end of life, the most popular subject was opioid rotation (46%).


Although the basic knowledge of physicians was adequate, there seemed to be a lack of knowledge in several areas, which can be a barrier for good pain management at the end of life. From this study four areas emerge, in which it seems likely that an improvement can improve the quality of pain management at the end of life for many patients in the Netherlands: 1)palliative sedation; 2)expected effect of opioids on survival; and 3) opioid rotation.

¿qué opinais? es interesante?, todos conocemos desde atención primaria el uso adecuado de los mórficos? Hemos abandonado los mórficos y estamos usando fármacos mucho más caros en tiempos de crisis???.

Espero vuestras respuestas y opiniones si estais interesados.


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